Tuesday, October 23, 2012

Cleveland Browns outgoing president Mike Holmgren doesn't rule out return to coaching

BEREA, Ohio -- Instead of riding off on his Harley-Davidson into the sunset, outgoing Browns president Mike Holmgren just might roar up to another head coaching job.

Holmgren, who will leave the franchise at the end of this season -- or before -- admitted in his exit press conference Tuesday that he's still infected by the coaching bug and almost sounded as if he regretted not coaching here.

Does he have one more stint left for that playoff-studded 23-year coaching resume?

"I don't know," he said. "I know this: I learned a lot of things in the last three years. One of the things that I thought I knew and now I'm sure, I do miss the coaching part of it. I really do, so ..."

So why didn't Holmgren, 64, descend from his ivory tower in Berea and don the whistle again in 2010 after firing Eric Mangini? For starters, no one really twisted his arm.

"I thought about it," he said. "At the time we were compiling a list of coaching candidates, I asked [GM Tom Heckert], the selection people, the guys who were involved in that, I said 'you don't have to say yes, but tell me tomorrow, should I be on the list?' And, I don't know if they were afraid to come to me and say, 'Are you kidding, an old guy like you, you shouldn't be on that list.' But they didn't. It gave me a chance that evening to think about it a little bit more and I did what I did."

What he thought about and discussed with his wife Kathy, was that perhaps he wasn't up for an all-consuming return to the field.

"At that particular time, I wasn't ready to do it again," he said. "I thought I'd be shortchanging the organization."

But what he discovered was, as president, how often he felt utterly helpless.

"What happens on the field, you have no control over really," he said. "You're just watching. Whereas when I was coaching, I always thought there was some way I could fix this."

Now that his job has been cut short by two years -- he was in the third year of a five-year deal that pays him about $8 million a year -- Holmgren feels there's more football left in him.

"I'm leaving it open," he said. "I said this was my last great adventure. I thought it was going to be longer and so we'll see what happens. My first goal is, if I can, help this team and these coaches this season. Then I'm going to sit back and catch my breath and look around a little bit and see what happens."

Holmgren made no guarantees he'll stick around through the season, which is what owner Jimmy Haslam initially said he planned to do. With new CEO Joe Banner hanging his shingle on Thursday, Holmgren realizes it might be awkward.

"We're going to take it a day at a time and see how it goes," said Holmgren. "My emphasis is going to be the football side of it. I don't have to do the business stuff any more. If I can help one player be a little bit better this season or one coach be a little bit better and I feel I'm contributing, then that could happen."

Holmgren, who was never offered a credible role with the new regime but understands why, has assured Haslam and Banner he won't be a distraction.

"I'm not gonna rock the boat," he said. "I'm not gonna get in anybody's way that way. I think I can help a little bit, but if it gets cumbersome or uncomfortable for anybody, then, heck, I don't want that to happen."

He hasn't made his pitch to Banner yet, but has extolled the virtues of coach Pat Shurmur and Heckert to Haslam.

"Jimmy knows what I feel about them," he said. "I don't think you can get a better general manager than Tom Heckert. I think he's tremendous. Hard-working guy, great personality, knows the college players, knows how to put a winning team together. He's very, very good.

"And Pat is a bright, new coach who's had to go through some stuff that not many of us had to go through when we were starting out. I believe in him as well."

He feels he left the Browns a better place, in part, because of emerging rookie quarterback Brandon Weeden, whom he believes is a franchise quarterback. "I think so. I really do. I think Brandon is off to a good start. He's an excellent passer. I like how he leads.

"People don't cut him quite as much slack because he's 29. [But] he's done very well and I think there's a bright future because we've -- the organization has found its quarterback."

Holmgren, who profusely thanked Randy Lerner for the opportunity, is proud of overhauling the organization and infusing the roster with young talent. His biggest regret is not seeing it come to fruition yet.

"I so much wanted to put a product on the field and win some games for Randy Lerner," he said. "He certainly deserved that. I wish we'd won a few more games [but] I think there's light at the end of the tunnel."

The Browns are 10-29 since Holmgren took over. He said there were no regrets about the youth movement this year -- 26 of 53 players have one or two years' experience.

"I know how we were trying to build the team and I wouldn't change that," he said. "I'm hoping the table is set for the future."

He apologized for snapping at the media a few days after Colt McCoy's concussion last season and warning reporters not to come to him for playoff tickets -- a sound bite that's been played over and over.

"It wasn't my proudest moment," he said. "I apologize to you. I shouldn't have said it." Then he added with a smile, "so because I've confessed this to you, may I phone you for tickets when the time comes?"

Holmgren's legacy will include creating the Browns Ring of Honor and reviving the Legends program. It will include a two-year rift with Hall of Famer Jim Brown that he repaired this season. Ultimately, it could include the foundation for success, which would mean he was one himself.

"I think we're close, I really do," he said. "We've been in every ballgame this year really, and I think it's gonna be OK. I honest-to-goodness feel there are good times ahead -- soon. And I'll be rooting hard for this group from wherever I am in the next couple of years, because I think it will happen."

That's something Haslam and Banner could get revved up about.

On Twitter: @marykaycabot

Source: http://www.cleveland.com/browns/index.ssf/2012/10/cleveland_browns_outgoing_pres.html

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EUR/USD: Euro rose buoyed by Spanish elections, trading lower ...

GCI Forex News - EUR/USD: Euro rose buoyed by Spanish elections, trading lower this morning

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EUR USD

EURUSD Movement

For the 24 hours to 23:00 GMT, EUR rose 0.38% against the USD and closed at 1.3071, after Spanish regional election results indicated support for the austerity policies of Prime Minister, Mariano Rajoy.

On Sunday, the Spanish Prime Minister, Mariano Rajoy won elections in his home region of Galicia, a boost for his austerity-focused government that removed a potential obstacle to him asking for a bailout.

Adding to the positive sentiment, the European Commission stated that it hopes Greece and its international creditors would reach an agreement within next few days to get its next tranche of bailout funds.

The Euro was also buoyed after the European Central Bank (ECB) Executive Board member, Joerg Asmussen, stated that the ECB would do everything it can to show that the Euro is irreversible.

According to a survey by the Conference Board, the leading economic index in Germany declined 0.3% (MoM) to 102.3 in August, after a 0.2% fall in the previous month.

In the Asian session, at GMT0300, the pair is trading at 1.3053, with the EUR trading 0.13% lower from yesterday?s close, after Moody?s Investors Service lowered its rating on Catalonia and four other Spanish regions.

The pair is expected to find support at 1.3024, and a fall through could take it to the next support level of 1.2995. The pair is expected to find its first resistance at 1.3083, and a rise through could take it to the next resistance level of 1.3113.

Trading trends in the pair today are expected to be determined by the release of business climate in France and Euro-zone?s consumer confidence.

The currency pair is showing convergence with its 20 Hr and 50 Hr moving averages.

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Source: http://forexnews.gcitrading.com/currencies/eurusd/eurusd-euro-rose-buoyed-by-spanish-elections-trading-lower-this-morning.htm

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The 5 Ways to Optimize Your Email Marketing for Mobile | Business ...

Don?t Forget the Smart Phone!

why you need to mobile optimize your email marketingWe?ve all heard the now familiar and slightly gross statistic pictured to the right: 4.8 billion people worldwide own a cell phone, while only 4.2 billion own a tooth brush. It?s shocking just how much mobile phones are taking over our lives. Smart phones and internet-enabled devices are experiencing the largest area of growth. The phenomenon of iPhones has grown 10 times faster than the last technology revolution, America Online. If you?re using email marketing to nurture your leads into clients and your clients into repeat sales, you can?t ignore mobile optimizing.

Over 75% of smartphone users are reading emails on their phones regularly. If you fail to send out emails they can open and read, chances are they might not open the content in the future. We?ve compiled several useful tips and tools to ensure the 91% percent of American adults who keep their cell phones in reach 24/7 won?t miss your message:

1. Ditch the Tiny Links

Unlike the days when a cursor was the primary means of web navigation, your leads? fingers are going to be their primary method for smart phone navigation. If you want your links to get clicks, they can?t be difficult to access or hard-to-see. Make your links visible and accessible by prominently placing call-to-action buttons that even the clumsiest smart phone user can?t avoid clicking.

2. Get Your Timing Right

It?s probably not hard to realize that email marketing efforts sent out on a Monday morning might get buried. Timing is everything when it comes to email marketing, and research by Return Path has found that your open rate could very well correlate with smart phone usage, particularly if your buyer personas tend to be pretty plugged-in. Mobile email typically remains steady during the work week, though usage is highest on Fridays and Saturdays. Use tapers on Sunday. It goes without saying that only you can determine what days and times work best for your market. Track your open rates, click-throughs and other analytics to determine when your segments easiest to engage.

3. Test and then Test Some More

Do your images load correctly? Can you easily open the links and does the layout display well?? Check it on a variety of different devices ? if you can test out both tablets and smart phones, all the better. Just because your email marketing effort looks gorgeous on your graphic designer?s computer screen doesn?t mean it?s going to be quite as appealing on a much-smaller smart phone. Some experts recommend keeping your images between 500-600px wide, though some Blackberries can?t display anything larger than 320 px.? Make sure no one is stuck waiting for your email template to load, because they?ll likely lose interest during that period of time.

4. Don?t Beat Around the Bush

Put yourself in the shoes of your smart phone-using buyer personas. They?re most likely pretty busy, enough so that they?re multi-tasking and opening emails on the go. You can?t afford to waste their time with extraneous language or irrelevant information. If you haven?t ditched the boring company newsletter, built buyer personas and started segmenting your? email list, don?t delay these crucial steps and risk the hit to your sender score if someone marks the message as spam. Wondering how to really hit a home run? Let them know your offer or discount? is only available for mobile users. e-Dialog research has found that maneuver results in an 18% mobile opt-in average.

5. Keep Your Subject Lines Really Short

35 characters. That?s less than 1/3 the length of a Tweet and it was typically the recommended length for an email subject line in the days before mobile was so predominant. It?s hard to communicate much in such a short phrase, especially considering that research has found that your open rate will soar if you describe your offer in an accurate and enticing way. Are you starting to sweat? Too bad, because mobile-optimizing your email marketing dictates even shorter subject lines that jive well with smaller screens. 15 characters is thought to be a good target by some email marketing experts.

6. Test the Text, too

While most smart phones can read and display an email marketing campaign in HTML, some aren?t quite smart enough to open that format. Make sure you text out the text version of your email. Make any necessary edits you need to ensure that the links are big enough to use and images have been removed.

Mobile email is not going anywhere. As smart phones continue to get smarter and their owners continue to become busier, the rate at which we check, read and send emails from our phones will keep soaring. Radicati Group estimates that by 2016, over 730 million accounts will be regularly accessed from smart phones. Don?t ignore the impact this segment could have on your bottom line! Optimize with clear Ctas, clean text and short, snappy subject lines.

New Call to action

Source: http://www.business2community.com/online-marketing/the-5-ways-to-optimize-your-email-marketing-for-mobile-0309170

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Monday, October 22, 2012

A whale with a distinctly human-like voice

ScienceDaily (Oct. 22, 2012) ? For the first time, researchers have been able to show by acoustic analysis that whales -- or at least one very special white whale -- can imitate the voices of humans. That's a surprise, because whales typically produce sounds in a manner that is wholly different from humans, say researchers who report their findings in the October 23 issue of Current Biology, a Cell Press publication.

"Our observations suggest that the whale had to modify its vocal mechanics in order to make the speech-like sounds," said Sam Ridgway of the National Marine Mammal Foundation. "Such obvious effort suggests motivation for contact."

It all started in 1984 when Ridgway and others began to notice some unusual sounds in the vicinity of the whale and dolphin enclosure. As they describe it, it sounded as though two people were conversing in the distance, just out of range of their understanding.

Those unusually familiar sounds were traced back to one white whale in particular only some time later when a diver surfaced from the whale enclosure to ask his colleagues an odd question: "Who told me to get out?"

They deduced that those utterances came from a most surprising source: a white whale by the name of NOC. That whale had lived among dolphins and other white whales and had often been in the presence of humans.

In fact, there had been other anecdotal reports of whales sounding like humans before, but in this case Ridgway's team wanted to capture some real evidence. They recorded the whale's sounds to reveal a rhythm similar to human speech and fundamental frequencies several octaves lower than typical whale sounds, much closer to that of the human voice.

"Whale voice prints were similar to human voice and unlike the whale's usual sounds," Ridgway said. "The sounds we heard were clearly an example of vocal learning by the white whale."

That's all the more remarkable because whales make sounds via their nasal tract, not in the larynx as humans do. To make those human-like sounds, NOC had to vary the pressure in his nasal tract while making other muscular adjustments and inflating the vestibular sac in his blowhole, the researchers found. In other words, it wasn't easy.

Sadly, after 30 years at the National Marine Mammal Foundation, NOC passed away five years ago. But the sound of his voice lives on.

Audio file of whale: http://www.eurekalert.org/multimedia/pub/48866.php?from=224114

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Story Source:

The above story is reprinted from materials provided by Cell Press, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Sam Ridgway, Donald Carder, Michelle Jeffries, Mark Todd. Spontaneous human speech mimicry by a cetacean. Current Biology, 2012; 22 (20): R860 DOI: 10.1016/j.cub.2012.08.044

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/EHg1DKoiJqc/121022122052.htm

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Stem cell bodyguards: Rare immune cells keep blood stem cells youthful

ScienceDaily (Oct. 22, 2012) ? Hiding deep inside the bone marrow are special cells. They wait patiently for the hour of need, at which point these blood-forming stem cells can proliferate and differentiate into billions of mature blood immune cells to help the body cope with infection, for example, or extra red blood cells for low oxygen levels at high altitudes. Even in emergencies, however, the body keeps to a long-term plan: It maintains a reserve of undifferentiated stem cells for future needs and crises. A research team headed by Prof. Tsvee Lapidot of the Institute's immunology Department recently discovered a new type of bodyguard that protects stem cells from over-differentiation. In a paper that appeared in Nature Immunology, they revealed how this rare, previously unknown sub-group of activated immune cells keeps the stem cells in the bone marrow "forever young."

Blood-forming stem cells live in comfort in the bone marrow, surrounded by an entourage of support cells that cater to their needs and direct their development -- the mesenchymal cells. But the research team, which included postdoctoral fellow Dr. Aya Ludin, Prof. Steffen Jung of the Immunology Department and his group, and Ziv Porat of the Biological Services Unit, discovered another type of support cell for the stem cells. These are an offshoot of the macrophage family -- literally the "big eaters" of the immune system that are important, for instance, for bacterial clearance. The team found that a rare sub-population of the bone-marrow macrophages has another role to play. Each of these rare macrophages can take a stem cell under its wing and prevent its differentiation.

Probing more deeply, the researchers revealed, in precise detail, how these macrophages guard the stem cells. They secrete substances called prostaglandins, which are absorbed by the stem cells. In a chain of biochemical events, these substances delay differentiation and preserve the youthful state of the stem cells. In addition, the prostaglandins work on the neighboring mesenchymal cells, activating the secretion of a delaying substance in them and increasing the production of receptors for this substance on the stem cells, themselves. This activity, says Lapidot, may help the non-dividing stem cells survive chemotherapy -- a known phenomenon. Macrophages also live through the treatment, and they respond by increasing their prostaglandin output, thus heightening their vigilance in protecting the stem cells.

The bodyguard macrophages also increase their activity in times of infection. While other members of the macrophage family are recruited to fight the pathogens, their cousins in the bone marrow are hard at work ensuring that a pool of stem cells will resist the urge to differentiate.

In previous work in Lapidot's lab, it was discovered that prostaglandin treatments can improve the number and quality of stem cells. This insight is currently being tested by doctors in clinical transplantation trials for the use of stem cells from umbilical cord blood to treat adult leukemia patients. These trials are showing that prior treatment with prostaglandins improves migration and repopulation potential, enabling the small quantities of cord blood stem cells to better cure the patients. "The present study hints at the possibility of further increasing the support for bone marrow stem cells by exploring this intriguing connection between the immune cells and stem cells," says Lapidot. "An understanding of the mechanisms at work in these cells might improve the success of stem cell transplantation, especially that of umbilical blood."

Share this story on Facebook, Twitter, and Google:

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Story Source:

The above story is reprinted from materials provided by Weizmann Institute of Science.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Aya Ludin, Tomer Itkin, Shiri Gur-Cohen, Alexander Mildner, Elias Shezen, Karin Golan, Orit Kollet, Alexander Kalinkovich, Ziv Porat, Gabriele D'Uva, Amir Schajnovitz, Elena Voronov, David A Brenner, Ron N Apte, Steffen Jung, Tsvee Lapidot. Monocytes-macrophages that express ?-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nature Immunology, 2012; 13 (11): 1072 DOI: 10.1038/ni.2408

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/_IOohmboVyU/121022113605.htm

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ALA encourages librarians to give a shout out to libraries on Digital ...

Digital Learning DayThe American Library Association is once again supporting Digital Learning Day as part of our continued effort to shine the light on the work libraries do every day to support digital literacy. Digital Learning Day, sponsored by the Alliance for Excellent Education, is the culmination of year-long activities in K12 schools, public libraries, and among educators from all walks of life. This year?s culminating event in Washington, D.C. on February 6, 2013, will celebrate educators who collaborate to create inspirational learning opportunities for young people by effectively integrating technology use and practices in and out of the classroom.

Through our ongoing work with the American Library Association?s Office for Information Technology Policy (OITP) Digital Literacy Task Force we have learned about the critical role librarians play in developing resources for classroom teachers, guiding students through the difficult challenges of digital citizenship, teaching administrators and library boards about the powerful learning opportunities afforded by appropriate technology use, and supporting the continuing education of their peers. We have heard stories about the challenges librarians grapple with to provide rich experiences to their patrons (experiences that they know are possible and in many cases necessary): school librarians who struggle with the reality of filtering in the school environment that inhibits what students can access online and blocks the collaborative tools that can be used to create content and work with peers; public librarians who often juggle their responsibilities to help new computer users navigate online resources; and academic librarians who continually motivate students to take advantage of the support and research resources available through the library.

Fortunately, librarians are a tenacious bunch and we have a broad collection of success stories and examples of best practices. Just this year, OITP recognized the team at New Canaan High School in Connecticut for its integration of tools like Facebook, iPads, Twitter, and Google Apps into multi-disciplinary projects where students are encouraged to take charge of their own learning and are becoming solid digital citizens.

Many public libraries are responding to the needs of their patrons by developing a suite of options for digital literacy and skill-building support. Queens Public Library in New York offers formal computer classes using the resources created by library staff, as well as on demand and self-paced online tutorials for patrons and classes on using social media. Other libraries are bringing classes and resources into the community such as the Free Library of Philadelphia with its Hot Spots program that uses wired spots located throughout the city to offer access to computers, printers, the Internet, reference materials from the Free Library, and trained staff to provide one-on-one guidance. The library also is seeking community partners to connect with its Techmobile, the library?s 25-foot vehicle outfitted for digital literacy training and outreach.

In an effort to reach students and make them aware of the resources offered in academic libraries, academic librarians are striving to work closely with university administrations and professors to integrate information literacy skills into the student learning process. For example, at the University of Tennessee in Chattanooga, librarians helped to write the basic English curriculum, making sure that the standard course ? which reaches 78 percent of freshmen ? aligned with the Association of College and Research Libraries information literacy standards.

Now it?s your turn. What is your library doing that should be highlighted as part of recognizing the important work going on every day in all types of libraries? Help spread the word and participate in this year?s Digital Learning Day. The Digital Learning Day Website lists numerous ways you can participate but here are a few: submit your story or video that shows innovative teaching and learning; write a blog about your experiences; or plan an activity on Digital Learning Day and share a video on the website.

Give librarians the shout out they deserve.

Source: http://www.districtdispatch.org/2012/10/ala-encourages-librarians-to-give-a-shout-out-to-libraries-on-digital-learning-day-2013/

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