Brad Pitt has it made in the shade! To add some flair to his classic black tuxedo and crisp white dress shirt, the 48-year-old actor strolled the red carpet at the "Killing Them Softly" screening in Cannes, France, on Tuesday sporting Sama Eyewear's $1,250 frames.
Alberto Pizzoli / AFP - Getty Images
Brad Pitt in Cannes, France, on Tuesday.
VOTE: Do these four-eyed stars look better with or without glasses?
The luxe aviator-style sunglasses, which are made from 100 percent pure titanium, feature mirrored lenses that are vapor coated in pure 18k rose gold. The style, called "Black Onyx," is also available in yellow gold, platinum and kohl.
This isn't the expensive sunnies' first tinseltown appearance; Pitt debuted the pair in his Oscar-nominated flick "Moneyball."
PHOTOS: Brad Pitt's sexiest movie looks of all time
At the screening's after party sponsored by Johnnie Walker Blue Label, Pitt, who got engaged to his partner of seven years Angelina Jolie in April, took off his shades and kicked back for a "pre-bachelor party" where he was joined by Chris Tucker, P. Diddy and his costar Ray Liotta. At the mostly-male fete, the group enjoyed cigars and $390 bottles of Johnnie Walker whisky.
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The United States Navy foresees a future where the rising cost of oil will create operational vulnerabilities. In response, it has devised a massive online game to crowd source innovative ideas from the public to sink its energy challenges.
Researchers at the Navy?s Naval Postgraduate School and the Institute for the Future, a California non-profit focused on sustainability issues, today announced an upcoming game called EnergyMMOWGLI. The game will launch starting tomorrow, Tuesday, May 22, and run for three days.
The game immerses players in a dystopian year 2022; energy security is costly (a barrel of oil costs as much as a dishwasher) and resources are strained. Players battle with their wits by brainstorming how to diversify energy supply with alternative fuels, increase efficiency, and reduce overall fuel consumption.
EnergyMMOWGLI is ?an examination of what our energy future looks like if we fail to act now. Every day that petroleum prices increase, it erodes our ability to train for and execute operations that our nation demands of us. Little by little, that results in decreased combat capability, and that is something we simply cannot accept,? said Cmdr. James Goudreau, director of the Navy Energy Coordination Office.
Another game announced last year focused on devising strategies to combat the rising threat of piracy along trade routes. The scenario was set off the coast of Somalia, and over 16,000 players registered to participate.
The Navy is embracing a trend known as ?serious gaming,? which has entered both business and government organizations. My friend and past colleague Alex Handy today wrote about how a Gartner research study found that more than 50 percent of business that manage ?innovation processes? will ?gamify? those processes by 2015.
Serious gamers have been gathering for an annual summit since 2004 to discuss the ramifications of gameplay upon society. One of its initial participants was Alcoa, which uses gaming to instruct workers how to safely operate forklifts.
The Navy is also taking its gaming very seriously. ?We hope to increase the awareness of energy security as a national security issue as well as stimulating discussion that will allow the Navy to achieve greater energy resiliency and combat readiness,? Cmdr. Goudreau said.
British singer Cheryl Cole, left, and U.S. actress Cameron Diaz pose for photographers as they arrive for the European premiere of the movie 'What to Expect When You're Expecting' at a cinema in London, Tuesday, May 22, 2012. (AP Photo/Matt Dunham)
British singer Cheryl Cole, left, and U.S. actress Cameron Diaz pose for photographers as they arrive for the European premiere of the movie 'What to Expect When You're Expecting' at a cinema in London, Tuesday, May 22, 2012. (AP Photo/Matt Dunham)
British singer Cheryl Cole, right, and U.S. actress Cameron Diaz pose for photographers as they arrive for the European premiere of the movie 'What to Expect When You're Expecting' at a cinema in London, Tuesday, May 22, 2012. (AP Photo/Matt Dunham)
British singer Cheryl Cole, right, U.S. actress Cameron Diaz, center, and actress Anna Kendrick pose for photographers as they arrive for the European premiere of the movie 'What to Expect When You're Expecting' at a cinema in London, Tuesday, May 22, 2012. (AP Photo/Matt Dunham)
U.S. actress Cameron Diaz signs autographs as she arrives for the European premiere of the movie 'What to Expect When You're Expecting' at a cinema in London, Tuesday, May 22, 2012. (AP Photo/Matt Dunham)
British singer Cheryl Cole, left, and U.S. actress Cameron Diaz pose for photographers as they arrive for the European premiere of the movie 'What to Expect When You're Expecting' at a cinema in London, Tuesday, May 22, 2012. (AP Photo/Matt Dunham)
LONDON (AP) ? The stars of the romantic comedy "What to Expect When You're Expecting" had plenty of praise for each other ? and a warning about making out on the hood of a car ? during the film's British premiere in London on Tuesday.
Cameron Diaz, Chace Crawford and Matthew Morrison, Anna Kendrick and Rodrigo Santoro were among the actors who walked the red carpet at the British Film Institute's IMAX theater.
The film ? inspired by the bestselling book by Heidi Murkoff, and also featuring Jennifer Lopez, Dennis Quaid, Cheryl Cole and Chris Rock ? looks at love through the eyes of five interconnected couples as they experience pregnancy and childbirth.
Kendrick and Crawford were one of the couples with some steamy moments in the film. But the reality wasn't quite that great, Kendrick said.
"The scene where we kind of make out on the hood of a car, it all looks pretty sexy and cool and fun, but I would not recommend trying to do that," she said. "It is uncomfortable. My legs were covered in bruises the next day. So I hope that it looks really nice, but it was actually quite a painful experience."
Director Kirk Jones gave high marks to Diaz, saying she was "phenomenal" in the scene where she gave birth.
"The concern as the director is always that you turn up on set, and an actress doesn't want to give her all because she'll be thinking, 'I don't want to look too sweaty, I don't want to look too red, you know, I don't want to really go for this,'" he said. "But she went for it, in a big way, yeah."
Diaz's onscreen partner Matthew Morrison also praised her, this time for her dancing skills.
"There's this one part where she wraps her legs around me, and I have to spin her around, and I said, 'Hold me tight because I don't want to, like, drop you and it's gonna help with me turning you around,'" he said. "And she squeezed me so hard I couldn't even breathe. It was, like, 'Damn it, let go, let go.' She's so strong, she's so strong."
Singer and former "X Factor" judge Cole takes on her first acting role in the movie as a judge in a celebrity dance-off contest.
Diaz gave her a thumbs-up, saying, "She played it beautifully, she was fun and entertaining and she provided a great energy for the set."
"What to Expect When You're Expecting" open in the U.K. on Friday.
Bias found in mental health drug research presented at major psychiatric meeting Public release date: 22-May-2012 [ | E-mail | Share ]
Contact: Kara Gavin kegavin@umich.edu 734-764-2220 University of Michigan Health System
Patient care nationwide may be affected when research on medications contain only 'good news' especially when the research is industry-funded
ANN ARBOR, Mich. When thousands of psychiatrists attend their field's largest annual meeting each year, the presentations they hear about research into drug treatments report overwhelmingly on positive results.
That's the finding of a new study published in the Journal of Clinical Psychopharmacology by two young psychiatrists from the University of Michigan and Yale University, who analyzed the presentations given at two recent meetings of the American Psychiatric Association.
Of 278 studies presented at the 2009 and 2010 APA meetings that compared at least two medicines against each other for any psychiatric illness, they found that 195 had been supported by industry, and 83 funded by other means. The authors then evaluated the studies without knowing which kind of support each one had.
Of the industry-supported studies, 97.4 percent reported results that were positive toward the medicine that the study was designed to test, and 2.6 percent reported mixed results. No industry-sponsored studies with negative results were found.
In contrast, when industry was not the source of funding, 68.7 percent of the presentations were positive, and 24.1 percent contained mixed results, while 7.2 percent contained negative results.
This 'presentation bias', in which mostly good news about medicines gets reported at meetings, echoes the 'publication bias' that has been seen in research published in major journals, says Srijan Sen, M.D., Ph.D., an assistant professor of psychiatry at the U-M Medical School who led the study while in his residency at Yale.
While attending the APA's massive annual meeting, he noted the large industry presence and emphasis on research involving medicines that were still "on patent" and being actively marketed to both psychiatrists attending the conference. He teamed with Yale psychiatry resident Maya Prabhu, M.D., M.Sc., now a consulting forensic psychiatrist at Yale, to do a formal review.
"This analysis suggests that the APA meeting might be being used as an opportunity to make drugs seem more effective than they are," he says.
Meanwhile, research on "talk therapy" treatments such as cognitive behavioral therapy which doesn't have industry backing gets less attention, even though there is growing evidence that such non-drug therapies can have as much effect as medicines in illnesses such as depression.
Since the APA meeting is a major source of continuing medical education credit for psychiatrists, and a hub for psychiatry residents just starting out in the field, the bias has the potential to affect their clinical care when they return home.
Sen notes that the research journals and funding agencies have tried to confront research bias in journal articles by requiring pharmaceutical companies to register the clinical trials they are conducting and include the registration number when publishing the study. This allows interested individuals to see which trials are being reported in the medical literature, and whether the trial results are interpreted according to the original study design.
For instance, if a drug trial is designed to test long-term results from a particular treatment, but a paper is published showing positive results over a much shorter term, that could be an indication of bias. Research meetings could require a similar practice, Sen says. And, APA could be more selective in accepting poster presentation submissions.
If nothing else, Sen says, attendees at the APA's meeting and perhaps other large gatherings of psychiatrists should be aware of the positive bias of the research they will hear about at the meeting.
And, non-industry funding for research especially research to compare older "off patent" drugs that aren't being marketed by industry is also important, he says. The federal government has funded large comparison studies in depression, schizophrenia and bipolar disorder, he notes and these mostly showed that the generic medications that have lost their patent protection are just as effective as newer, patent-protected ones. But even still, psychiatrists prescribe the generic ones far less often than the brand-name patent-protected ones.
###
The study was supported by grants MH095109 and UL1RR024986 from the National Institutes of Health. In 2009, Sen was a trainee member of an APA committee involved in soliciting the
scientific reports to be presented at the annual meeting.
Reference: Journal of Clinical Psychopharmacology & Volume 32, Number 3, June 2012
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Bias found in mental health drug research presented at major psychiatric meeting Public release date: 22-May-2012 [ | E-mail | Share ]
Contact: Kara Gavin kegavin@umich.edu 734-764-2220 University of Michigan Health System
Patient care nationwide may be affected when research on medications contain only 'good news' especially when the research is industry-funded
ANN ARBOR, Mich. When thousands of psychiatrists attend their field's largest annual meeting each year, the presentations they hear about research into drug treatments report overwhelmingly on positive results.
That's the finding of a new study published in the Journal of Clinical Psychopharmacology by two young psychiatrists from the University of Michigan and Yale University, who analyzed the presentations given at two recent meetings of the American Psychiatric Association.
Of 278 studies presented at the 2009 and 2010 APA meetings that compared at least two medicines against each other for any psychiatric illness, they found that 195 had been supported by industry, and 83 funded by other means. The authors then evaluated the studies without knowing which kind of support each one had.
Of the industry-supported studies, 97.4 percent reported results that were positive toward the medicine that the study was designed to test, and 2.6 percent reported mixed results. No industry-sponsored studies with negative results were found.
In contrast, when industry was not the source of funding, 68.7 percent of the presentations were positive, and 24.1 percent contained mixed results, while 7.2 percent contained negative results.
This 'presentation bias', in which mostly good news about medicines gets reported at meetings, echoes the 'publication bias' that has been seen in research published in major journals, says Srijan Sen, M.D., Ph.D., an assistant professor of psychiatry at the U-M Medical School who led the study while in his residency at Yale.
While attending the APA's massive annual meeting, he noted the large industry presence and emphasis on research involving medicines that were still "on patent" and being actively marketed to both psychiatrists attending the conference. He teamed with Yale psychiatry resident Maya Prabhu, M.D., M.Sc., now a consulting forensic psychiatrist at Yale, to do a formal review.
"This analysis suggests that the APA meeting might be being used as an opportunity to make drugs seem more effective than they are," he says.
Meanwhile, research on "talk therapy" treatments such as cognitive behavioral therapy which doesn't have industry backing gets less attention, even though there is growing evidence that such non-drug therapies can have as much effect as medicines in illnesses such as depression.
Since the APA meeting is a major source of continuing medical education credit for psychiatrists, and a hub for psychiatry residents just starting out in the field, the bias has the potential to affect their clinical care when they return home.
Sen notes that the research journals and funding agencies have tried to confront research bias in journal articles by requiring pharmaceutical companies to register the clinical trials they are conducting and include the registration number when publishing the study. This allows interested individuals to see which trials are being reported in the medical literature, and whether the trial results are interpreted according to the original study design.
For instance, if a drug trial is designed to test long-term results from a particular treatment, but a paper is published showing positive results over a much shorter term, that could be an indication of bias. Research meetings could require a similar practice, Sen says. And, APA could be more selective in accepting poster presentation submissions.
If nothing else, Sen says, attendees at the APA's meeting and perhaps other large gatherings of psychiatrists should be aware of the positive bias of the research they will hear about at the meeting.
And, non-industry funding for research especially research to compare older "off patent" drugs that aren't being marketed by industry is also important, he says. The federal government has funded large comparison studies in depression, schizophrenia and bipolar disorder, he notes and these mostly showed that the generic medications that have lost their patent protection are just as effective as newer, patent-protected ones. But even still, psychiatrists prescribe the generic ones far less often than the brand-name patent-protected ones.
###
The study was supported by grants MH095109 and UL1RR024986 from the National Institutes of Health. In 2009, Sen was a trainee member of an APA committee involved in soliciting the
scientific reports to be presented at the annual meeting.
Reference: Journal of Clinical Psychopharmacology & Volume 32, Number 3, June 2012
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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Public release date: 22-May-2012
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